Donating Bone Marrow and Platelets (and Blood! and Organs ! and Umbilical Cord Blood !) Oh My!

Why Register to Donate Marrow?

Every year, thousands of adults and children need bone marrow transplants -- a procedure which may be their only chance for survival. Although some patients with aplastic anemia, leukemia or other cancers have a genetically matched family member who can donate, about 70 percent do not. These patients' lives depend on finding an unrelated individual with a compatible tissue type -- often within their own ethnic group -- who is willing to donate marrow.

There is a critical need for more volunteer donors. Many patients, especially people of color, cannot find a compatible donor among those on the registry. Patients and donors must have matching tissue types, and these matches are found most often between people of the same ethnic group. A large, ethnically diverse group of prospective donors will give more patients a chance for survival.

 

What is Marrow?

Marrow is the tissue found inside bones that produces red blood cells, white blood cells and platelets. These vital blood cells fight infection, carry oxygen and help control bleeding. Any disease that attacks the marrow can eliminate the body's ability to protect itself.

 

Who Can Donate Marrow?

If you are in good health and between the ages of 18 and 60, you may be eligible to join the NMDP's registry, where patients seeking a compatible donor begin their search.

 

Steps to Donating Marrow: How Can I Join the Registry?

  • If you live in any area of the United States, call the    National Marrow Donor Program  at 1-800-MARROW-2 or your local Red Cross Agency. If you are outside of the US, please call the nearest hospital or your family doctor and ask them to refer you to the correct institution. .

  • Clinics register volunteers who wish to join the registry. After completing a questionnaire, a small sample of blood is drawn and your inherited tissue type (HLA, or human leukocyte antigen type) is determined. The laboratory results are entered into the NMDP's registry, a computerized database of potential donors.

  • If you match the tissue type of a patient seeking a donor, additional testing will confirm the results. You will meet with marrow donor counselors in the Bone Marrow Donor Program of your choice, who will help you make an informed decision about donating marrow.

  • The marrow collection process usually does not require an overnight stay in the hospital. The procedure itself is painless, because it is performed under anesthesia. But, for an average of two weeks following the procedure, most donors experience sore hips.For some donors, activities may be restricted for a few days. Most donors also report that donating marrow is a very positive experience. Many marrow donors are willing to donate again in the future.
  • The donated marrow is transfused to the patient, whose diseased cells have been destroyed by intensive chemotherapy. In time, the donated marrow engrafts and begins producing healthy blood cells.

 

Why are More People of Color Needed?

Because patients are most likely to find a compatible donor within their own ethnic group, a diverse group of potential donors is needed. Over 3 million volunteers have joined the national registry. Of the 2,700,000 donors whose race is known, 28% are people of color.

Percentage of ethnic groups on the national registry

Total Where Race is Known

African American 9.8%
Asian / Pacific Islander 7.2%
Hispanic 9.4%
Native American 1.6%
Caucasian 71.5%

 

Funding

When someone volunteers to join the national registry of potential donors, a blood sample is taken and is tissue-typed. This test costs $60. Because funding is limited and the need to diversify the registry is so critical, the U.S. government pays the fee for people of ethnic minorities. Money to cover the cost to test Caucasian volunteers usually must be donated by the individual or others. Is $60 too much? How many of us would spend that on two meals or less out with the family?

Once a donor is found to match a patient, the donation is paid for by the NMDP and billed to the patient and transplant center.

Transplant Registries

The Nuts and Bolts of Bone Marrow Transplants

NOTDAW topics

Bone Marrow Donations and the Red Cross

Bone Marrow Centers in Germany

About stem cell transplants

 

Information taken from © 1998  Mississippi Valley Regional Blood Center  All rights reserved.

Aspheresis - Platelet donation

Many lifesaving medical treatments require platelet transfusions. Cancer patients, those receiving organ or bone marrow transplants, victims of traumatic injuries, and patients undergoing open heart surgery require platelet transfusions to survive. Because platelets can be stored for only five days, the need for platelet donations is vast and continuous.

Platelet transfusions are needed each year by thousands of patients like these:

 

Heart surgery patient 6 units
Burn patient 20 units
Organ transplant patient 30 units
Bone marrow transplant patient 120 units

 

What are Platelets?

Platelets are blood cells that help control bleeding. When a blood vessel is damaged, platelets collect at the site of the injury and temporarily repair the tear. Platelets then activate substances in plasma which form a clot and allow the wound to heal.

What is Apheresis?

Apheresis (ay-fur-ee-sis) is a special kind of blood donation that allows a donor to give specific blood components, such as platelets. During the apheresis procedure, all but the needed blood component are returned to the donor.

Why is Blood Separated?

Different patients need different types of blood components, depending on their illness or injury. After you donate whole blood, the unit is separated into platelets, red cells and plasma in our laboratory. Only two tablespoons of platelets are collected from a whole blood donation. Six whole blood donations must be separated and pooled to provide a single platelet transfusion. However, one apheresis donation provides enough platelets for one complete transfusion -- that's six times the amount collected from a whole blood donation.

Who Can be an Apheresis Donor?

If you meet the requirements for donating blood, you probably can give platelets. Apheresis donors must:

  • be at least 18 years old
  • be in good health
  • weigh at least 110 pounds
  • not have taken aspirin or products containing aspirin 72 hours prior to donation.

Are Apheresis Donations Safe?

Yes. Each donation is closely supervised throughout the procedure by trained staff. A small percentage of your platelets are collected, so there is no risk of bleeding problems. Your body will replace the donated platelets within 72 hours. The donation equipment (needle, tubing, collection bags) are sterile and discarded after every donation, making it virtually impossible to contract a disease from the process.

How Does the Procedure Work?

Blood is drawn from your arm through sterile tubing into a centrifuge. The centrifuge spins the blood to separate the components, which vary in weight and density. A port is opened along the spinning tubing at the level containing platelets. These platelets are drawn up into a collection bag, while the remaining blood components (red cells and plasma) are returned to you through your other arm.

How Long Does it Take?

Depending on your weight and height, the apheresis donation process will take approximately 70 minutes to two hours. You may watch television or videotapes, listen to music, or simply sit back and relax while helping to save a life.

Donating - Main menu

Please call your local blood bank and ask about apheresis!!

ORGAN DONATIONS

Most people I know who have no objections on religious grounds say "I'd like to give my organs to be donated when I die" but do they do anything about it? Make sure your close relatives know your wishes (and your exact wishes about ressucitation, etc..), and even better, have it written in your will (if you have one) and also register to be an organ donor when you register for your drivers' license. (I think most DPS do this.) Make sure your relatives know, most of all, for most wills are not read until after you are gone - and most organs are no longer viable that long after death. Find out about regulations in your area. It only takes a few minutes, but can prolong someone else's life, give them sight, or help them live fuller lives! Next time you visit your doctor, ask him/her about details of how to do this in your community.

A Word to the Pregnant among you!

Please, please ask your doctor about saving the umbilical cord blood when your baby is born! It is rich in "stem cells" - those rich, life-giving cells that haven't decided what to become yet. They are on the forefront of new treatments in medical science at the moment and can be used only if you ask the doctor to keep them, donate them or use them in some way. Otherwise, they go in the trash and help no one. Especially if you have a lot of cancer in your family! Ask your obstetrician about details and regulations in your community.


Last updated November 01, 2001 15:03:16

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